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Story. (taken from Wii booklet)

Caduceus International Timeline
The Following is a brief history of the Caduceus International Medical Organization.

LATE 1970'S
In response to a number of natural plagues, the Department of Health and Human Services sponsored the creation of a secret medical organization called CADUCEUS to help fight off the threat of disease.

1980
CADUCEUS INTERNATIONAL is established, which branches opening in Japan and Europe.

CIRCA 2007
"In order to create a stronger and more realistic medial organization for today's world," Secretary of Death and Human Services Richard Anderson succeeded in granting CADUCEUS USA complete independence from the United States Government. While still serving as CADUCEUS'S Executive Director, he ensured the organization could take action without having to wait for government approval.

CIRCA 2011
CADUCEUS JAPAN made great strides in eliminating the h5 influenza, while research from all branches led to a long-awaited cure for the AIDS virus. CADUCEUS INTERNATIONAL became the world's most influental medical organization.

2018
After minor restructuring, CADUCEUS INTERNATIONAL is well equipped to take on the medical challenges of the future. Analysts have predicted several possible threats and we are moving swiftly to ascertain the impact theur with have on world health.

Caduceus USA Surgeon's Manual:
Welcome! As a doctor at Caduceus USA,
you have accepted the mantle of Caduceus International's mission to improve the standard of health, worldwide.
This handbook should serve as a reference for some of the procedures you will encounter.
You will of course be required to keep up on the latest medical discoveries and techniques on your own time;
this is meant only as a brief refresher should you need it in the field.

               June 17, 2018

For over four decades,
Caduceus International has been the front line defense in the war against disease.
Though we have received great accolades for eradicating plagues such as the AIDS virus,
our work is never done-- we must remain ever vigilant.
A dangerous new threat has appeared on the horizon...

...it's called GUILT. (Gangliated Utrophin Immuno Latency Toxin).

Very little is known about this disease,
but rumor has it that GUILT is the first biological weapon used for "medical terrorism."
The virus mutates a cell of the victim's body,
which them mercilessly attacks the infected area until the victim dies.
Symptoms have wildly varied thus far,
and it seems unlikely that such a disease could occur naturally.
Though, who exactly could engineer GUILT is unknown at this time.

We've managed to keep GUILT hidden from the public thus far, but once it's revealed, the world will be depending on Caduceus to eliminate the threat. At this point, we do not have any viable treatments to combat GUILT; studying the virus must be our utmost priority.